CD38 anticorps
Aperçu rapide pour CD38 anticorps (ABIN6568082)
Antigène
Voir toutes CD38 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human CD38 (NP_001766.2).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- CD38
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Sujet
- The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
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Observed_MW: 45kDa
Calculated_MW: 13kDa/34kDa
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ID gène
- 952
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UniProt
- P28907
Antigène
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